Monthly Archives: June 2014

Opioid Induced Constipation – OIC

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Most patients require strong pain relief after their operations. Opioids (that is, narcotics or morphine-like medications) are usually a part of the pain management strategy postoperatively…and all medications come with side-effects.

Most postoperative pain management is multimodal – using multiple medications in small doses. The aim of that strategy is to target multiple receptors to maximise benefit and minimise side-effects.

When strong pain medication is required, it is important to identify those patients particularly at risk of constipation. Risk factors include advanced age, female sex, relative immobility, dehydration, altered nutritional intake, anal fissures and mechanical obstruction. Many of these are associated with a hospital stay…

Prevention and management of OIC includes

–       identifying patients at particular risk

–       dietary management – adequate hydration, dietary fibre

–       mobilisation – where possible

–       tailoring different types of opioids to patient needs  – and knowing that those needs change with time

–       pharmacological management: bulking agents, stool softeners, osmotic and/or stimulant laxatives.

 

Post-op cognitive decline and dementia: what’s the story?

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Postoperative cognitive decline (POCD) is a worry – and older patients are recognised to be at increased risk. The underlying mechanism and the specific contribution of anaesthesia remains unclear.

Further study is ongoing to establish the extent of POCD, why it occurs and what we can do to prevent it.

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“Current data do not support significant changes in practice other than avoiding purely elective procedures” ( http://www.medscape.com/viewarticle/745128 ).

HOW ABOUT ALZHEIMER’S?

Early studies in mice indicated that it was surgery, rather than anaesthesia that had a greater impact on a dementia-vulnerable brain. How this translates to humans (with or without dementia) is not yet known.

It is unlikely that anaesthesia is an independent risk factor for the development of dementia ( http://www.medscape.com/viewarticle/804439 ).

Meanwhile, the results of ongoing research in the areas of prevention and treatment of POCD are eagerly awaited by a growing sector or older patients in our community and the surgeons and anaesthetists who care for them…